On 14 February 2022, an article was published in the prestigious Nature Communications journal entitled “Mesenchymal stem cells transfer mitochondria to allogeneic Tregs in an HLA-dependent manner improving their andmmunosuppressive activity”.
The authors of the study include researchers from the PolTREG S.A. in cooperation with the University of Gdańsk and the Medical University of Gdańsk.
The work involves interactions of mesenchymal cells with TREGS cells. Scientists described the phenomenon of mesenchymal cells “lending” mitochondria to TREGS lymphocytes, which significantly increases the activity of the latter and may be used in therapy. The use of the phenomenon is also the subject of patent applications, of which PolTREG S.A. is a co-owner.
Link to the article (available free of charge):