The Japan Patent Office has granted PolTREG a patent for the intrathecal administration of its proprietary PTG-007 Treg cellular therapy for multiple sclerosis.

Injecting Treg cells directly in the spinal fluid – and not in the bloodstream – has shown superior results, PolTREG has found in its earlier studies in treating neurodegenerative diseases, as it bypasses the blood-brain barrier.

PolTREG is planning to launch two Phase 1/2a clinical trials for PTG-007, one in each of two forms of multiple sclerosis (MS): relapsing-remitting MS and primary-progressive MS.

PolTREG received a flurry of patents late last year as it continues to explore the full potential of Treg cells in fighting a flurry of autoimmune diseases.